Research profile
My group is interested in exploring gene function using computational techniques including algorithms and databases (existing or developed by us). Generally, we have a focus on studying the mechanisms involved in human disease with the goal of facilitating the development of better therapies. We work among other topics on the prediction of the function of proteins with a focus on compositionally biased regions, repeats and disorder, the study of protein interaction networks, the development of methods to aid the interpretation of transcriptomics data, and the prediction of transcript regulation and function. The results of our work are often distributed as software or online web tools.
I am interested in the IQCB because of its multi-disciplinary approach to research and its focus on topics that include machine learning and quantitative analysis of large and complex datasets, which align very well with the topics of research of our group.
Biography
Positions held
Since 2014
Professor of Bioinformatics, Johannes Gutenberg University (JGU), Mainz
Since 2008
Affiliate investigator at the Ottawa Hospital Research Institute
2014 – 2018
Adjunct Director, Institute of Molecular Biology (IMB)
2007 – 2014
Scientist (tenured since 2010) at the Max Delbrück Center for Molecular Medicine, Berlin, Germany
2006 – 2008
Early Senior Scientist, Molecular Medicine department, Ottawa Health Research Institute
2003 – 2008
Assistant Professor, Department of Medicine, Division of General Internal Medicine, Faculty of Medicine, University of Ottawa
2003 – 2006
Scientist at the Molecular Medicine department, Ottawa Health Research Institute
1998 – 2003
Staff scientist at the European Molecular Biology Laboratory, Heidelberg, Germany
1994 - 1998
Postdoctoral researcher at the European Molecular Biology Laboratory, Heidelberg, Germany, European Bioinformatics Institute, Hinxton, Cambridge, UK, and Centro Nacional de Biotecnología of the Consejo Superior de Investigaciones Científicas, Madrid, Spain
Education
1994
PhD in Biochemistry, Universidad Complutense de Madrid, Spain
1989
BSc and MSc in Biochemistry, Universidad Complutense de Madrid, Spain