My group is interested in uncovering hidden layers of RNA regulation by combining experimental innovation with bioinformatic analysis. More specifically, we use long-read nanopore sequencing, which enables us to capture full-length transcripts, detect processing intermediates, and investigate the RNA modification landscape associated with individual RNA molecules. One area we are currently exploring in more depth is ribosome biogenesis. In this context, we have developed NanoRibolyzer, a tool designed to quantify pre-rRNA species and analyze their processing sites and epitranscriptomic profiles. 

More broadly, my team and I are interested in continuing developing computational tools that simplify nanopore sequencing analysis and make complex datasets more accessible to the wider research community. 

Our research interests and expertise align closely with the aims of the IQCB. Since we use nanopore sequencing extensively and are actively developing new analytical tools, being part of the IQCB would be highly valuable for our group, particularly with regard to support for data storage, data handling, and computational infrastructure. At the same time, our combined expertise in RNA biology, nanopore sequencing, and computational analysis could provide a valuable contribution to the IQCB community. 

Positions held

Since 2023      
Principal Investigator within DFG collaborative research center “RNA Modification and processing” (TRR 319 RMaP) 

2022 – 2026 
Junior group leader at the Institute for Pharmaceutical and Biomedical Sciences, JGU Mainz 

2021 – 2022 
Postdoc at the Institute of Human Genetics, University Medical Center, Mainz  

Education

2016 – 2021 
Dr. rer. nat. in Biology, Johannes Gutenberg University Mainz, Germany 

2015 
MSc in Genetics and Microbiology, University of Sheffield, UK 

2011-2014     
BSc in Genetics and Microbiology, University of Sheffield, UK