Research profile
We are interested in studying the immune system and the tumor microenvironment (TME) using computational approaches. As immune cells highly interact with cancer cells, our mission is to better understand this interaction and how, for example, tumor cells evade the immune system’s response. To address such questions, we utilize single-cell, spatial, and genomic sequencing technologies (NGS) for analysis. Integrating various omics layers as well as clinical parameters, we seek to create a holistic view that creates new insights for basic research as well as clinical translation.
Biography
Positions held
Since 2023
Assistant Professor, University Medical Center Mainz , Institute of Immunology, Quantitative Biomedicine (AG Imbusch)
Since 2018
Teamleader, Teamleader for Computational Oncoimmunology , Applied Bioinformatics (AG Brors)
2017 - 2018
Consultant, GeneWerk GmbH, Heidelberg, Development of improved bioinformatics workflow for viral integration site detection (Dr. Annette Deichmann)
2016 - 2017
Consultant, BioMedX Innovation Center, Heidelberg, Consultant for bioinformatics analysis for Team: Epigenetics and COPD (Dr. Renata Jurkowska)
2014 - 2017
Bioinformatiker, Applied Bioinformatics (AG Brors), Heidelberg, NGS Analysen, Methodenentwicklung zur Unterscheidung von ’Driver’ und ’Passenger’ Mutationen in Krebs
2012 - 2013
Bioinformatiker, Data Management Group (AG Eils), Heidelberg, Verwaltung und Aufbereitung von Ergebnisdaten der deutschen ICGC Projekte Aufsetzen und Instandhaltung einer lokalen cBio Instanz
2011 - 2012
Junior Consultant, Intershop Communications AG, Jena, Erweiterung des Customer Information Centers (CIC) im Bereich Visualisierung und Benutzerfreundlichkeit, R&D im Bereich Datenmigration auf Oracle Basis
Education
2023 - 2024
MBA, Mannheim Business School, Executive MBA 2024 graduate
2017 - 2019
PhD Bioinformatik, Applied Bioinformatics (AG Brors), Heidelberg, NGS Analysen (Epigenom und Transkriptom) von regulatorischen T Zellen
2004 - 2010
Bioinformatik Studium, Friedrich-Schiller-Universität, Jena