Research profile

In my group we explore how epigenetic alterations contribute to the adaptation to stress and impact aging. In healthy, young cells heterochromatin represses repetitive elements and lineage specific genes. External stresses can alter heterochromatin and across evolution aging correlates with a reduction and reorganization of heterochromatin. We make use of the comprehensive genetic tools established in C. elegans and combine them with genomics and quantitative microscopy. With the goal to better understand the complex interplay between stresses experienced throughout life, the epigenome and aging. 

Biography

Positions held 

Since 2022   
Group Leader, Institute of Molecular Biology (IMB), Mainz

2013-2022   
Postdoctoral Researcher, Friedrich Miescher Institute, Basel


Education

2013   
PhD in Cell Biology, Max Planck Institute of Immunobiology and Epigenetics, Freiburg

2009   
Diploma in Biology, Albert-Ludwigs University, Freiburg

2006   
Vordiploma in Biology, RWTH Aachen University