Research profile
In my group we explore how epigenetic alterations contribute to the adaptation to stress and impact aging. In healthy, young cells heterochromatin represses repetitive elements and lineage specific genes. External stresses can alter heterochromatin and across evolution aging correlates with a reduction and reorganization of heterochromatin. We make use of the comprehensive genetic tools established in C. elegans and combine them with genomics and quantitative microscopy. With the goal to better understand the complex interplay between stresses experienced throughout life, the epigenome and aging.
Biography
Positions held
Since 2022
Group Leader, Institute of Molecular Biology (IMB), Mainz
2013-2022
Postdoctoral Researcher, Friedrich Miescher Institute, Basel
Education
2013
PhD in Cell Biology, Max Planck Institute of Immunobiology and Epigenetics, Freiburg
2009
Diploma in Biology, Albert-Ludwigs University, Freiburg
2006
Vordiploma in Biology, RWTH Aachen University