The main research focus of my laboratory is the context- and cell type-specific regulation of chromatin, with a particular emphasison the ATP-dependent BAF chromatin remodeling complexes. We aim to elucidate the subtype- and cell type-specific functions of these remodelers in gene regulation and beyond in different contexts, including development, tissue homeostasis, and ageing. Wealso use organoid models to study the molecular mechanisms by which mutations in BAF-encoding genes lead to cancer and neurodevelopmental disorders. In addition to large-scale microscopy and proteomics experiments, we frequently perform various types of next generation sequencing (NGS) experiments at the bulk and single cell level. These large datasets and their integration require extensive computational analysis, which fits well within the scope of the IQCB.

Positions held 

Since 2021   
Group leader in the Centre of Healthy Ageing, Mainz, Germany Max Planck Graduate Center, Junior Faculty Member, Mainz, Germany

Since 2020   
Group leader, Institute of Molecular Biology (IMB), Mainz, Germany

2016 - 2020   
Postdoctoral Researcher, Research Center for Molecular Medicine of the Austrian Academy of Sciences, CeMM, Vienna, Austria

Education

2012 - 2016   
Doctoral thesis, Institute of Molecular Biology (IMB), Mainz, Germany

2008 - 2012   
Master in biomedicine, Johannes Gutenberg University (JGU), Mainz, Germany Diploma in biology, Johannes Gutenberg University (JGU), Mainz, Germany

2006 - 2008   
Bachelor in molecular biology, Johannes Gutenberg University (JGU), Mainz, Germany